– Biotechnology, Cochin University of Science and Technology, India 2009, B.S. – Molecular Medicine, Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, India 2011, M.S. Research Focus Understanding the mechanistic roles of oncogenic proteins in B cell receptor signaling in mantle cell lymphoma (MCL) Dissecting the function of MCL-specific oncogenic proteins in new genetic mouse models for MCL Education 2019, Ph.D. Ngo is an award recipient of the American Society of Hematology Scholar Award, the Gabrielle’s Angel Foundation for Cancer Research, the Department of Defense’s Career Development, and the Concern Foundation for Cancer Research. Ngo joined the Department of Systems Biology where he will use innovative functional genomics tools and powerful animal modeling using relevant patient-derived lymphoma samples to gain new insights into critical signaling pathways that are important in lymphomagenesis and resistance to therapy. His laboratory has discovered an important role for recurrent mutations of cyclin D1, which results in deregulated protein turnover and therapy resistance in mantle cell lymphoma. Ngo was recruited to start his independent laboratory in the Division of Stem Cell and Leukemia Research at Beckman Research Institute of City of Hope. He then joined the laboratory of Louis Staudt at the National Institute of Health, National Cancer Institute for postdoctoral training, where he developed an expertise in large-scale functional genomics research, using RNA interference technology to identify functionally important pathways that harbor oncogenic mutations driving lymphomagenesis in diffuse large B cell lymphomas. degree in the laboratory of Jason Cyster at the University of California San Francisco, where he studied the molecular basis of lymphoid tissue organization through interactions of lymphocytes with stromal cells and the chemokines and cytokines they secret.
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